The mandates and core functions of the Commission are provided under section 5(1) of the Universities Act Cap. 346. These functions can be clustered into the following three major areas
To conduct regular and impromptu periodic evaluation of universities, their systems and programmes so as to regulate the quality assurance systems at new and established universities and in the process, institutions are registered and accredited to operate in Tanzania. TCU also validates and evaluates programmes to ensure their credibility for recognition of university qualifications attained from local and foreign institutions for use in Tanzania.
Advisory Function
To advise the government and the general public on matters related to higher education in Tanzania as well as international issues pertaining to higher education, including advice on program and policy formulation and other best
 practice
To ensure the orderly conduct of university operations and management adherence to set standards and benchmarks, by providing support to universities in terms of coordinating the admission of students, offering training and other sensitisation interventions in key areas like quality assurance, university leadership and management, fund raising and resources mobilisation, entrepreneurial skills and gender mainstreaming.